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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1596104405d9e62382673ecedd46a3130d933f3217de2cbdb285ffe7a8b021f' 
  AND token = 'gBZ5NEeJ2O8wndfR3WLQZtu0BP4VjNwLzde5Rjeod00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}