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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '130d39b819b2d0cb4ab7d2d4a8f163b0bd684e7144ea14c16713181118094952' 
  AND token = 'T5ZHfuBSFZd2Hx8Pfjq+2+523cTIjpgPmivLNMVSFEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}