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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f54e8c46b372e7a72f49d0e930308180db500dae680d8caf31c0f8a9440fcf6' 
  AND token = '7rMVcXufsVmbOEUAB+hbPup8BBjcewDJir0yVN9kDe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}