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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a72f644a62f957b9265ddacee60dbe24b5719771ea9008dfbbb40216015ddfe' 
  AND token = 'VUhpUn4R0+gosGBVrY1dl3n37xTwm4Jfdrl/T0amgQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}