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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13880f3c078cf5394273535a8c0548b7a0858de662f602c112c7395aa7e81d79' 
  AND token = 'py/QEr3z0MR9Oeh9E/w/dLGkgQfO1hzB1NCZNyB2BYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}