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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f18c401ecc70a5f73289fad068c9cfcebf9d873c6978152a31b51f7141466173' 
  AND token = 'euuuDEvVVW8pD+6E/1eH7PFeAOPpaCvxex7sd5TcfEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}