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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22afaf68b063c633c082fd46371823308f22861cc9ab150ca876d369b08e8bdc' 
  AND token = 'NwzlWNchG6NopJF6c1CoAPBpC6RLuHY5dpArUnECNE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}