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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb9cdb64cd51c25b28ae316550d7d0f596dc0aee1c4749c451955853e98c5cb' 
  AND token = 'bcKb8k0059z9P1EHOTLu69hmAx/lcx6t93Rdtgh4TOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}