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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e04d022925f0ddf0079816a582970fd482436d4d6b7c5f3aae0690d03cec26' 
  AND token = '/46K58peIFKV85SHxKPtPN2NRJnBq5nT1T+C3NU21AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}