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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4bfa345d46ab196be8682f702c7b3c91ad8695bdc297d7e45ddc911d39b5434' 
  AND token = 'alemmYi5tYUGD7HXI2XD4fQOFui6dkClO2+JMzSYaPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}