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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9797451b6da3dabf6cf717a7407bd1bc0bdc23fdd91c9cc2429b07fc86ad414c' 
  AND token = 'G9z6MH2jDawj6Yt/bQxTs24VxOS24jDMW13GmEJdLAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}