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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15c9c678c220b29cd0a4d47fdf38141ac17e45b3d4d6d131e2d81fadefb33618' 
  AND token = 'XFbE4zd7/P2SLoP9IdETHsDcK33NCk+iX79doP+US8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}