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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb95aa83931a6e3d7d92f9737578c6cb8f0efac0fbefff170e3e1bb8593392a' 
  AND token = 'oObGIV9C+Xbi0TLRh5pBRFDCLxbG5XETD9l2tE0alyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}