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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5817391ee883fb8c0e6f8f934fb16ed0790b697f33384c42ff9191fbf02f7c7' 
  AND token = '0Fgyl1T3pyWL2aHUemiiib9lwOk8b8E5VQHUnXQ/md8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}