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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a735602a19a48f7e24370922d4ce10c121fbcad65c8452247c1492b87aa257' 
  AND token = 'dMonrZwrOcc1Tc8FD0kh5U/pR8WW7Kokxw8F+DiRurM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}