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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a51507f8c385e0d13c1377c6e28edbf5153fffd75d42f1761de734e1c4fc44ea' 
  AND token = 'JemITLHmofaJiQYs+qGHpIKywPpaIidOqRprEc4Njwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}