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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cdeb62fb646613d0f456c60d0a932a20b68dc756ece3a72117df9ba07ad19d0' 
  AND token = 'cqBAx+9TZN4d3YqEFnJX0c3oEwS5rRI7DyK/hwyFS4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}