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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '410ae071c11217fab3f2e1d801fcdc531451ecf2009874c397fe309f6675e94d' 
  AND token = 'dveXXqUd9PqjgK3MVHN1UvPSlLr4z9TlfTJ0NpvB/eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}