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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52d45132dd90f9275eff93fbc3ee5a6c242a7e742bf6bc6d8d649aecf164defc' 
  AND token = 'kNRNMsgr5ZeWIb3U6is4t2B/98EdUmvKBLVxwRFRA2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}