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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbf0b787f9af2b6a8e66f44c075be0663c11765baea6b40eecd4a68b363e2ac8' 
  AND token = 'G1XVj3ALRcp7g9PlSXvVLhrv7JB+p3Cf8E3+bh6TrVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}