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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19fb98d48bb2399896e415a2335a990ce5a29d55abd299af625e40ffe54c0c6' 
  AND token = 'nwGP5M+NdjzgXOJNNg1pFfdpWgR4CkQeBBINlcyMqsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}