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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78cb1fb72e61ea4add8bd39e992e8c0d9e34bae456a9cb9bbb5ce7487c11785e' 
  AND token = 'V6wTF8K6b8zUFWckRf6yYcZBAEixa+PFVICFgphn9sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}