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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b7dc6c70ed69d55b33b4d51f4a686b11c9532baa57f86b8daf4455cd22ad0af' 
  AND token = 'o8tyxE1iYD0c8Wpe10i88fB5e5ZxTet9qKKPsG0n6Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}