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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377411d42784b965ecc7b0ea830e3dc10374eb2c51e60df457a1f51e828fdd33' 
  AND token = 'gYiA3MtyfYxG0oxVjVIWFJif3TL83rup1VfMOp+Cxys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}