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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01dc09cea82c325fd79517291615f0e6a4fb62b74793adbd9822255e544d6457' 
  AND token = 'CSlK6SK2IkIWnW1RNLHEITG9g7b0wVksg7tTY09rMOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}