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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04e0a62f21afce842b5f9b79cd202bb8f862f51c886ffee97e1d6f204e37a1b2' 
  AND token = 'cCbKrLaw3btVfUSDMc5/v9x/aRv1Zxv1fkY34u+Q8cY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}