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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d2384f4e8a6d1ffb583de8684146dfa62826b3dede8f36ad2c4d7a1d2167882' 
  AND token = 'FDD9DXTKl/FBAW959lDrkA5SWt71y1pFNgCfwM26Xd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}