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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79e24f6fb61b31fecff02a99d1d0e7426c8cd4645b89c8fbc6c449568b1b4302' 
  AND token = 'ZkN38bhbTPMISNrXzZaqWLdnKVBlXsK/FA0GNIL3f+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}