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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '820d65ce1032940a604254737abd8c35c6cffe19cc800fc0380a8dd821665fb9' 
  AND token = 'Hq/F3ez6f+1mymvH+KgFcU1o9vzA4Cb0H53+cCOPHfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}