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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a919abac110709b2d04ffdd122f38e1d93f54a723967bfdb8dfc7e5e4902bd' 
  AND token = 'b0ZsdoOBnSEOcvw9YhI5+V170jCbnep7xvNYJT7NqpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}