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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9136509525429cbecb5470bc0c1a9e531339e802bbe1d0d9966e7dfe78d84be6' 
  AND token = 'jFhn+BJl1Bze8gljEsyB6fe8CyBUo/JykyIkfGr44VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}