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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d6b8388446edb83e19db549f578658602de6c6978e215d3f72aa930b328e87' 
  AND token = 'Ga9LRmpSpmLXkfJ6EC7GT99qJmgFJDQHUJz7PmQnVNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}