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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '426d867ae2720a08e193136dda477d55072abeefc26f4db46666a1be7e241260' 
  AND token = 'Ks/SkTux33weY223whDj/f+ANy3+hYXgzfIoQ3kgx/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}