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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7b450fbbf58d9d9cf4bbc1d1e772445bc15eb91bb7cc73df7e62dd592dbd20' 
  AND token = '1ryqO8FvQPsiDoVO2s3WkPOW24N2fwW32YCptcdaM1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}