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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf82b5d23654683dc6240c9b8d02167902271d8bc5004a77993bfc8f574d1fb7' 
  AND token = 'bbAZA1dra8zSC+UqAWimsGfD+I7aqDeosAUyNctkpbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}