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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd5a38a952ff8151a8435fcf0b2b599ba8dcc4930a1c1b341e23212c36ecf0f' 
  AND token = '2PEpAwnNAdZ/djBYE5um3loLUWuaG0OfT6wfU+weaGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}