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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451c04dcf8543a334c1d672131111e945f973240456db3973962b0049560e9bd' 
  AND token = '7phtiy3jQ+C1f4Sk0EX++VGOVQDnr+rskeDdrSm/xlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}