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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c812c740c1781a3ae7892d2478812781fc3046a275e41624aec88dc300d68c53' 
  AND token = '3DWI3y9IUYIsyS4Cb2MWv3VJq7vmKTFkC49c3PYNiTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}