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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58f99b6741e7230c599b5820eb09c7989ae312449a33ec4c81777778ad9313a3' 
  AND token = 'NP/Zn5XiDnlGRsAnuZW73tZIVOOgwGo65HqD1z4bY58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}