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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4978e5c0243f85bcfae92cffe5ee04c49e52a28a4b39111c7c0e0c50ebc8e311' 
  AND token = 'eXvd2O2L8FkadIxsvwDPVtrkadUW9nPKgSgOqpYtjH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}