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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7f551d41e9c42b33c7caa93805b66b66c0a2d809148a248b032034835f9f78f' 
  AND token = 'U5tyuzEmWRZ2+ve8wjLugsDa32L8LwFtQDmeg4UuwRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}