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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e689aaa9051e4e13ec425b3e290020e8fd8b6728283aad9a5c370ef78f296de4' 
  AND token = 'XdEvRQK3GCvepTCfIAKakHG9ad3XkP4PsUAUKdhU0Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}