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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b42457705e753d9f5dd49c7943a05b2f405995b13d14a5929f19f2dbc99c4ef2' 
  AND token = 'DCZdzTBhH2CMAClXIXZ536xP3eivJyp/aAOa9P6aJ8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}