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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09fee568d2b6f49a9c1e34d00cf6b27829b1c35ab266b155f6e75a7eccc7fcfd' 
  AND token = '4w/c4Sm2DYPFYZBPDfQlZII1AYMxVjb8wDJoaT+mFOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}