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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1de90e56e59318e72c834bbe341c1005b6abf6a7525d00b037a9d3616cfb53f' 
  AND token = 'NrcDmhVMI9l1PUOkfldnoi+A7Ken5Klt9f94TgEZpEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}