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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f518d62e9e99da15bff09aec424e2ecd0882402039dd06d9971c0bc9c3bfe82b' 
  AND token = 'KBTBM+CbiYeeSMSBNNPim4xChRgmeNeND8/HadD2ERQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}