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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33243a0c284f876d81434fc94897537068de6424a04f9a54b302fa2450a8c0a3' 
  AND token = 'DWrAq+7zo7q7zS/viViSmrTJ1ZO3FM/b3qgyJPJ6IrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}