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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c972b453a37f260e738ec2500d35f0f420af210562b6351e2de60b0b5f61d6' 
  AND token = 'LcUu1qV7k8e2DsdN7NfvDJwpXsOR7V+bJyf2JP1E/zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}