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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e154a729dd2ae5d0fcd343be5808ac3e031d4095f630e903100aca375bcd70ee' 
  AND token = 'P/h8SgK5qZ8fpf4nqncGH/Qlz4vp9GjIELSjlqD/mdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}