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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2954f4ee25c516aa53a4dffd443bee66c29907a0b8217e23351ea1556d0c8c91' 
  AND token = 'CrurccMRn7d1cHvk9keGke4xc0l2VTHAsse2ZvSZAQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}